Abstract Search

ea0044ep97 | (1) | SFEBES2016

Graves’ disease with fluctuating thyroid status and hypothyroidism with positive anti-TSH receptor antibody levels – distinctive autoimmune side-effects following alemtuzumab therapy for multiple sclerosis

Pariani Nadia , Willis Mark , Muller Ilaria , Healy Sarah , Nasser Taha , Jones Joanne , Chatterjee V. Krishna K. , Dayan Colin , Robertson Neil , Coles Alasdair , Moran Carla

Alemtuzumab, a highly effective, newly-licensed, treatment for multiple sclerosis (MS), is notably associated with Graves disease (GD), which reportedly has an indolent course.Methods: Case record review of patients who developed thyroid dysfunction (TD) after alemtuzumab treatment in Cambridge & Cardiff, to determine type, frequency and course of TD.Results: 41.8% (104/249; 81F, 23M) of alemtuzumab-treated patients devel...

0 shares

ePoster

Endocrine Abstracts

Graves’ disease with fluctuating thyroid status and hypothyroidism with positive anti-TSH receptor antibody levels – distinctive autoimmune side-effects following alemtuzumab therapy for multiple sclerosis

BiosciAbstracts